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Neuroprotection

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Published by Lippincott Williams & Wilkins .
Written in English

Subjects:

  • Neurology & clinical neurophysiology,
  • Anesthesiology,
  • Medical / Anesthesiology,
  • Medical / Nursing

Book details:

The Physical Object
FormatHardcover
Number of Pages247
ID Numbers
Open LibraryOL11132312M
ISBN 100683183281
ISBN 109780683183283
OCLC/WorldCa37711029

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The Handbook of Neuroprotection serves as a comprehensive review of neuroprotection based on knowledge of the molecular basis of neurological disorders. Neuroprotective effects of older, established drugs, as well as new drugs in development, are well documented in this detailed volume, featuring the most cutting-edge and innovative methods 5/5(3). The proposed book is unique because it gives a comprehensive account of the neuroprotective and neurogenic effects of steroid and polypeptide hormones. Furthermore, new pharmacological approaches for treatment of neurodegenerative conditions are presented, based on the neuroprotective and neurogenic properties of natural and synthetic hormones. Neurodegenerative changes occurring early from primary acute immune-mediated inflammation support the hypothesis that multiple sclerosis (MS) is a complex disease. Axonal loss progresses with the disease course and represents the principal driver of disability. In this context, the pursuit of neuroprotective therapies in multiple sclerosis provides new valid alternatives that could Author: Juan Espinosa-Parrilla, Marco Pugliese, Nicole Mahy, Manuel JRodríguez. The Handbook of Neuroprotection serves as a comprehensive review of neuroprotection based on knowledge of the molecular basis of neurological disorders. Neuroprotective effects of older, established drugs, as well as new drugs in development, are well documented in this detailed volume, featuring the most cutting-edge and innovative methods Brand: Humana Press.

  There is growing interest in the field of melatonin research regarding its neurobiological mechanisms as well as its repercussions in clinical practice. Melatonin: Therapeutic Value and Neuroprotection explores melatonin’s neuroprotective effects and discusses the therapeutic potential of melatonin and melatonin agonists in treating . Neuroprotection: Models, Mechanisms and Therapies. Editor(s): Prof. Dr. Mathias Bähr; Following an overview of neurodegenerative, traumatic, and ischemic disorders, the book goes on to cover in vitro and animal model systems as well as cellular and molecular mechanisms. An extremely helpful analysis of clinical studies explains reasons for. Publisher Summary. This chapter discusses brain iron to understand its possible role in the pathogenesis of the neurodegenerative process and the potential of developing a neuroprotective therapy based on the concept of iron chelation. Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management.

  Neuroprotective strategies that limit secondary tissue loss and/or improve functional outcomes have been identified in multiple animal models of ischemic, hemorrhagic, traumatic and nontraumatic cerebral lesions. However, use of these potential interventions in human randomized controlled studies has generally given disappointing results. In this paper, . Neuroprotection by Nutraceuticals Alzheimer’s Disease Alzheimer’s disease is a progressive neurodegenerative disorder affecting older people, with a prevalence of approximately % in persons ages 65–69 years, % in ages 70–74, % in ages 75–79, % in ages 80–84, and % in persons 85 years and by: ISBN: OCLC Number: Description: xii, pages: illustrations. Contents: 1. Metabolic Failure and Oxidative Stress Contribute to Ischemic Neurological Impairment and Delayed Cell Death / Gary Fiskum Neuroprotection by Sodium Channel Blockade and Inhibition of Glutamate Release / Hugh C. Hemmings, Jr. . This initial issue of NeuroRx ® is devoted to the topic of neuroprotection, a concept based upon observations that biochemically induced neural cell death appears to play an essential role in virtually all forms of acute and chronic neurodegeneration. Initially proposed at the end of the 19th century, the concept of secondary or delayed tissue damage received strong experimental .